# CELIVION Lin J | hADM, ECM Composition & Allo-PELT | HEBE Canonical source: https://www.hebeintl.com/en/professional/celivion/ Language: en Publisher: HEBE / HEBE OF AMERICA # CELIVION Lin J Inside the world of biological matrix. Starting with human acellular dermal matrix: ECM architecture, matrix preservation and particle design. ## From tissue architecture to particle scale. Differences between aesthetic materials begin with the material itself. CELIVION Lin J starts with human dermal matrix: after cells are removed, attention turns to the remaining extracellular matrix and its processing into micronized freeze-dried powder. - 01 / ORIGIN ### Human dermal matrix Understand material origin, tissue sourcing and traceability. - 02 / MATRIX ### An extracellular network Collagen, elastin and GAGs provide a multi-component perspective on ECM. - 03 / PARTICLES ### Micronized, freeze-dried Move from the matrix to average size, D50 and product presentation. ## CELIVION Lin J. Start with the material. CELIVION Lin J is a freeze-dried powder product based on micronized human acellular dermal matrix (hADM), presented as 150 mg × 1 syringe. The brand uses ECM Skin Reviser as its material positioning. Its product information focuses on extracellular matrix (ECM) composition, Allo-PELT™ low-temperature decellularization and ECM Mix Cage™ particle management. ## ECM is a network of distinct components. hADM describes processed tissue matrix; ECM describes the extracellular structural components within that material. Collagen, elastin and glycosaminoglycans (GAGs) play different roles. The matrix should not be reduced to collagen alone. Collagen ≈ 82.8% Elastin ≈ 4.7% Glycosaminoglycans (GAGs) ≈ 0.23% Approximate composition values reported in the manufacturer’s materials describe material analysis, not percentages of clinical improvement or human treatment outcomes. ## Two technologies. Preservation and processing. ### Allo-PELT™ Allo-PELT™ expands to Preserved ECM at Low Temperature Processed. The described approach uses staged low-temperature cycles for decellularization, with a focus on retaining ECM composition and structure during processing. ### ECM Mix Cage™ ECM Mix Cage™ is the particle-processing and control technology named in the materials. It addresses tissue micronization, sizing and ratio management. Together with Allo-PELT™, it describes the processing path from tissue matrix to particles. ## Read the average alongside the distribution. Average particle size describes an overall statistical measure. D10, D50 and D90 are the diameters at 10%, 50% and 90% of the cumulative size distribution. D50 is not the average, and D90 is not a maximum particle diameter. Measure Reported value Average particle size 33.92 μm D10 3.23 μm D50 34.42 μm D90 61.82 μm Particle data describe the material; they do not establish treatment duration, human absorption rates or a guarantee of safety. Source update: Korean materials synchronized on 6 November 2026, including the CELIVION product brochure and catalogue. Edited by HEBE. Batch-specific specifications and storage requirements follow the product label and official instructions. ## CELIVION Lin J at a glance. CELIVION Lin J is a freeze-dried powder product based on micronized human acellular dermal matrix (hADM). Its introduction focuses on extracellular matrix (ECM), particle design and processing. Product materials list a 150 mg × 1 syringe presentation and a D50 of 34.42 μm. Product CELIVION Lin J Material Human acellular dermal matrix (hADM) Form Freeze-dried powder Listed presentation 150 mg × 1 syringe Median particle diameter, D50 Information & collaboration Contact HEBE ## Start with the material. Discover CELIVION. From human dermal matrix composition to low-temperature processing and particle design, CELIVION Lin J places the material at the centre of its product introduction. Understanding origin, structure and processing builds a clearer professional perspective. ## Meet CELIVION Lin J CELIVION Lin J is a powder-type product based on micronized human acellular dermal matrix (hADM). Derived from human dermal tissue, hADM is processed to remove cells and fat components while retaining extracellular matrix constituents including collagen, elastin and glycosaminoglycans (GAGs). ## Understanding ECM: the structural environment of skin The extracellular matrix (ECM) is the structural network surrounding cells. Understanding ECM helps explain differences in the composition, structure and processing of aesthetic materials. This material system is central to CELIVION’s product introduction. ### The architecture of ECM goes beyond one constituent. #### Collagen · Fibrous structure Collagen is a major structural protein in extracellular matrix. Understanding it means considering fibre form, arrangement and structural characteristics after processing, alongside its name. #### Elastin · Network composition Elastin is another constituent considered in ECM. Its structural role differs from collagen, supporting a multi-component view of dermal matrix. #### GAGs · Matrix environment Glycosaminoglycans are a class of polysaccharides in ECM. They extend the discussion beyond fibres to the surrounding matrix environment, rather than reducing ECM to collagen alone. ## From material to processing. A processing technology centred on low-temperature treatment and matrix preservation. A technology system focused on particle processing, sizing and ratio control. Material composition and particle design are key elements of the product’s technical introduction. ### Follow how the material is handled. CELIVION’s technology narrative follows two themes: Allo-PELT™ focuses on low-temperature processing and matrix preservation; ECM Mix Cage™ focuses on particle processing, sizing and ratio control. Read origin, processing and final form together. - 01 #### Origin Human dermal tissue and source traceability - 02 #### Decellularization Cell removal with attention to matrix constituents - 03 #### Particle design Processing, sizing and particle distribution - 04 #### Freeze-dried form Presentation and product instructions A material-reading pathway. Refer to technical product materials for manufacturing details. Two measures. Two ways to read particle size. ## 34.42 μm: a starting point for reading particles. Particle design is not explained by a smaller number alone. Average size describes one statistical characteristic; D50 marks the midpoint of the cumulative distribution. Read the full distribution, processing and requirements for use together. BIOBIJOU product materials report an average particle size of approximately 33.92 μm and a D50 of 34.42 μm. These are distinct statistical measures: D50 is the diameter at the 50% point of the cumulative particle size distribution. ## Processing with a focus on matrix preservation. Allo-PELT™ centres on stepwise low-temperature circulation decellularization, focusing on limiting heat-related changes to matrix structure. ECM Mix Cage™ addresses particle processing, sizing and ratio control. The technologies explain complementary aspects of the processing approach. ## What matters when reviewing product information? - Material origin, composition and product specifications - Processing methods and particle characteristics - Product instructions, requirements for use and tissue traceability - The specific conditions behind research and clinical experience ## Two professional perspectives, starting with the material. ### Skin quality & ECM support A professional assessment of skin structure, material distribution and skin quality. The presentation discusses this perspective as Skin Booster, with a focus on matrix support. ### Soft volume & contour transitions Professional planning around subtle volume transitions, tissue structure and contour continuity. This differs from a goal of substantial volumization and requires assessment of the area and material. These are professional discussion themes from the presentation. Applicable uses and methods depend on product instructions and local requirements. ## How do hADM, HA and synthetic material categories differ? Material category Starting point Professional assessment Human dermal matrix (hADM) A matrix material obtained after decellularization of human tissue, with a focus on ECM composition and structure. Traceability, processing, particle distribution, instructions and tissue response. Hyaluronic acid (HA) Hyaluronic-acid-based materials with product-specific crosslinking, concentrations and rheological properties. The individual product’s properties, intended areas and instructions. PLLA / PDLA / PCL / CaHA Distinct chemistries and material behaviours; the word collagen does not make these the same material. Particles, carriers, degradation characteristics and evidence for each product. This is a distinction between material categories, rather than a ranking of treatment outcomes. ## Four dimensions of a clearer product assessment. ### Goal Clarify whether the discussion concerns skin quality, structural support or contour transitions. ### Material Review hADM origin, ECM composition, presentation and traceability. ### Particles Read average size, D50 and the full distribution together rather than comparing one number. ### Professional assessment Consider the treatment area, tissue conditions and risk management with a qualified medical professional. ## Read product information, experience and research in context. Particle exploration on slide 6 is a preclinical animal pilot. Slides 9–18 include the speaker’s observations and professional approach. These help frame research questions but do not establish individual outcomes, recovery times or safety guarantees. - hADM material research · Ko et al., 2023 ↗ A mouse study comparing injectable and sheet-type hADM provides material research context. - Particulated hADM research · Lee et al., 2026 ↗ A 20-person, 20-week split-face trial used Elravie Re2O. It is not a CELIVION product trial. Content reference: Understanding hADM in Aesthetic Medicine, professional presentation dated 4 September 2026. Edited by HEBE; updated 17 October 2026. ## A closer look at CELIVION. What is hADM? hADM stands for human acellular dermal matrix. It refers to processed dermal matrix material, rather than a live-cell product. How are ECM and collagen related? Collagen is an important component of ECM. Other constituents include elastin and glycosaminoglycans. How can I learn about the product and professional collaboration? For CELIVION Lin J information, professional training or collaboration, contact BIOBIJOU in Korea through its official enquiry page or email biobijou@biobijou.co.kr. What is CELIVION Lin J? CELIVION Lin J is a freeze-dried powder based on micronized human acellular dermal matrix (hADM). Product materials list 150 mg × 1 syringe and focus on ECM material and particle processing. Is CELIVION Lin J hyaluronic acid? They are different materials. CELIVION Lin J is based on hADM, while HA products are based on hyaluronic acid. Composition and instructions must be reviewed for each product. Is hADM a stem-cell or exosome product? No. hADM is processed acellular dermal matrix. It should not be confused with live cells, stem cells or exosome products. What does D50 34.42 μm mean? D50 is the diameter at the 50% point of the cumulative particle size distribution. It differs from the average diameter. It describes particles, not duration of results or an independent safety guarantee. What do Skin Booster and Gentle Volumizing mean here? The presentation uses these terms for skin quality and ECM support, and for subtle volume support. Actual plans require product instructions, local requirements and professional medical assessment. Can I prepare or use it based on this webpage? No. Preparation, placement, dosing and aftercare are medical decisions that require product instructions and a qualified medical professional. How can I request CELIVION information and collaboration? ## Biological origin. Structural thinking. From origin to architecture, from matrix to particles. HEBE connects clear product information and professional dialogue with a deeper understanding of CELIVION Lin J and collaboration. ## Understand the material. Connect through expertise. ## Material information. Professional conversations. An event image from the synchronized Korean CELIVION materials shows the setting for product presentation and professional exchange. Product understanding remains grounded in material definitions, technical information and applicable instructions. ## Professional use and training materials The CELIVION Lin J User Guide is marked for healthcare professionals only and covers preparation, administration and aftercare. Professional institutions should check the applicable local requirements, corresponding product label and official instructions, including specifications, batch condition, storage and use requirements. This public page does not provide instructions for self-directed clinical preparation, drug mixing or injection. Qualified healthcare professionals can contact BIOBIJOU in Korea to confirm document versions and professional training arrangements. ## Questions about the updated CELIVION materials Are CELIVION LinJ and CELIVION Lin J the same product name? This page uses CELIVION Lin J consistently. The updated catalogue and packaging also use the joined form CELIVION LinJ. Both refer to the same product information here, rather than two different products. What does ECM Skin Reviser mean? ECM Skin Reviser is CELIVION’s brand positioning term for its material approach. This page explains hADM, extracellular matrix composition and processing; the term itself is not a regulatory classification or a clinical outcome. What collagen, elastin and GAG values are reported for CELIVION? The manufacturer’s composition analysis lists approximately 82.8% collagen, 4.7% elastin and 0.23% GAGs. These are material-analysis values, not percentages of clinical improvement. What are the reported D10, D50 and D90 for CELIVION? The materials list D10 at 3.23 μm, D50 at 34.42 μm and D90 at 61.82 μm, with average particle size at 33.92 μm. D values describe positions in the cumulative distribution, not maximum particle size. ## Before you get in touch What do Allo-PELT™ and ECM Mix Cage™ describe? In the CELIVION Lin J materials, Allo-PELT™ describes low-temperature processing and matrix preservation. ECM Mix Cage™ concerns particle processing, sizing and ratio control. These technology descriptions should be read alongside product specifications and instructions. Which CELIVION Lin J specifications should I review? Start with the material, form and presentation: human acellular dermal matrix (hADM), freeze-dried powder and 150 mg × 1 syringe. The listed D50 is 34.42 μm. Review the complete particle distribution, source traceability and product instructions with the specifications. Continue exploring - HEBE brand facts - International skincare curriculum ## Product enquiries and partnerships. Direct to Korea. HEBE edits the product information on this page. For CELIVION Lin J materials, professional training, supply and partnership enquiries, please contact the Korean seller BIOBIJOU directly. Email biobijou@biobijou.co.kr Phone +82-2-6235-9696 Address 경기도 하남시 하남대로 947, U1 CENTER A동 1516호, 12982 ## Source and related pages - https://www.hebeintl.com/en/professional/celivion/ - https://www.hebeintl.com/en/professional/ - https://www.hebeintl.com/en/professional/celivion/#cel-intro - https://www.hebeintl.com/en/professional/celivion/#cel-facts - https://www.hebeintl.com/en/professional/celivion/#cel-material - https://www.hebeintl.com/en/professional/celivion/#cel-tech - https://www.hebeintl.com/en/professional/celivion/#cel-perspectives - https://www.hebeintl.com/en/professional/celivion/#cel-compare - https://www.hebeintl.com/en/professional/celivion/#cel-research - https://www.hebeintl.com/en/professional/celivion/#cel-faq - https://www.hebeintl.com/en/professional/celivion/#cel-korea-overview - https://www.hebeintl.com/en/professional/celivion/#cel-korea-composition - https://www.hebeintl.com/en/professional/celivion/#cel-korea-process - https://www.hebeintl.com/en/professional/celivion/#cel-korea-particles - https://www.hebeintl.com/en/professional/celivion/#cel-korea-faq - https://www.hebeintl.com/en/professional/celivion/#cel-professional-use - https://pubmed.ncbi.nlm.nih.gov/37069348/ - https://pmc.ncbi.nlm.nih.gov/articles/PMC12985180/ - https://celivion.bio/ - https://www.biobijou.co.kr/bbs/write.php?bo_table=s5_1 - https://www.hebeintl.com/en/about/ - https://www.hebeintl.com/en/academy/international-skincare/